In order to integrate and evaluate many research resources and results, literature review and information extraction analysis were carried out to construct a lipid-lowering drug database to assist in promoting the research of lipid-lowering drugs in lipid-lowering and cancer treatment-related diseases, and to supplement the current collection of anti-hyperlipidemic drugs, including the number and classification of data collection. It covers the name, structural formula, structure, CAS number, relative molecular mass, type, target, cell line, cytotoxicity evaluation, tumor type, mechanism of action, reference year, reference title and corresponding website source of lipid-lowering drugs. The interface supports the query function of the above lipid-lowering drugs. Therefore, the lipid-lowering drug database will help to further find new indications for cancer treatment in addition to the efficacy of lipid-lowering drugs themselves from the idea of ' new use of old drugs '.