Bacteria-mediated tumor therapy (BMTT) has been used to control cancer for a long time, bacteria have shown great potential towards cancer therapy. The main mechanisms of bacteria against cancer cells are as follows: (i) reducing the nutrients required for the metabolism of cancer cells, (ii) enhancing human immunity, (iii) as a carrier for cancer therapeutic agents, (iv) releasing substances (v) forming biofilms, and (vi) invading and colonizing the solid tumor. In recent years, bacterial produced substances characterized to have potential anticancer activities and can serve as an antidote to cure deadly diseases such as cancer. Bacterial anticancer agents mainly include antibiotics, bacteriocins, non-ribosomal peptides, polyketides, toxins, etc. These are adopted different mechanisms of actions such as apoptosis, necrosis, reduced angiogenesis, inhibition of translation and splicing, and obstructing essential signaling pathways to kill cancer cells. Therefore, bacterially produced anticancer agents are expected to be a promising alternative in cancer therapeutics. This database contains 12 kinds of bacterially produced anticancer agents, including extracellular polysaccharide, extracellular vesicle, antibiotics, bacteriocin and so on, as well as their structural information, tumors targeted by them, mechanisms of bacteria-cancer-cell interaction and corresponding literature sources. The interface supports query functions, such as "species information of bacteria", "structure" and "activity evaluation value". This database can be used as an auxiliary tool to retrieve the data of anticancer agents produced by bacteria for drug discovery and clinical cancer management, thereby promoting the effective and sustainable using of anticancer agents drugs derived from microorganisms, reducing the research and development cost of repurposed drug and improving the survival rate of tumor patients.