This database focuses on drugs with urinary system toxicity and systematically integrates information on drugs that have been identified or potentially cause damage to the urinary system such as kidneys, bladder, and ureters in clinical practice and experiments. It covers core information including the basic attributes of drugs (generic name, chemical structure, structural formula, drug type, CAS number, relative molecular mass), clinical indications (e.g., anti-cancer, antipyretic, analgesic and anti-inflammatory, antibacterial), adverse reactions (e.g., acute kidney injury, interstitial nephritis, bladder irritation), toxicological mechanisms (including direct damage, oxidative stress, inflammatory response, accumulation of metabolites, etc.), as well as references and websites.The database aims to provide a convenient query and analysis tool for pharmaceutical researchers, clinicians, toxicologists, and pharmaceutical scientists. It facilitates the rapid identification of the urinary system toxicity risks of drugs, offers data support for drug safety evaluation, rational clinical drug use, and toxicological mechanism research, and promotes the precise prevention, control, and scientific management of drugs with urinary system toxicity.
