Fusobacterium nucleatum , a Gram-negative anaerobic bacterium commonly found in the oral cavity and the intestinal tract, has been confirmed to be closely related to the development of various malignant tumors such as colorectal cancer in recent years. F. nucleatum can accelerate tumor progression by regulating the host immune microenvironment, inducing chronic inflammation, and promoting gene mutations. It plays a key role in tumor metastasis and the formation of drug resistance. To deeply study the related gene mutations, this database is based on literature mining and multi-source data integration, focusing on the host gene mutation information related to F. nucleatum , and has included 456 relevant mutation entries, covering genomic locations of the mutated genes, mutation types, gene annotations, and references, etc. It provides important data support for clarifying the information of microbial-host genome interaction.
